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Dato-DXd by AstraZeneca and Daiichi Sankyo expected to drive market size of Antibody Drug Conjugates by 2034

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Dato-DXd by AstraZeneca and Daiichi Sankyo expected to drive market size of Antibody Drug Conjugates by 2034

January 23
08:28 2026
Dato-DXd by AstraZeneca and Daiichi Sankyo expected to drive market size of Antibody Drug Conjugates by 2034
Discover an in-depth Dato-DXd market report by a leading healthcare research firm, covering market landscape, growth trends, and forecast insights through 2034.

[Las Vegas, United States] DelveInsight, a leader in healthcare research firm, has recently published an in-depth report on Dato-DXd (AstraZeneca and Daiichi Sankyo) providing insights into the drug market landscape and market forecast of Dato-DXd upto 2034. The report, titled “Dato-DXd, Market Size, Forecast, and Emerging Insight – 2034” is now available for review and analysis.

 

Are you interested in finding out the projected market size of Dato-DXd in 2034? Dato-DXd Market Forecast

https://www.delveinsight.com/report-store/dato-dxd-sale-forecast-and-market-analysis

Key Factors Driving Dato-DXd Growth

1. Market Share Gains and New Patient Starts

  • Dato-DXd is emerging as a promising antibody-drug conjugate (ADC) in the solid tumor treatment landscape, especially for lung and breast cancers where there is a significant unmet medical need.

  • New patient initiations are expected to grow as oncologists increasingly embrace next-generation ADCs for patients whose disease has progressed after standard chemotherapy, immunotherapy, or targeted treatments.

  • Heightened interest from the oncology community is fueled by promising efficacy results in heavily pretreated patients, bolstering clinical confidence in the therapy.

  • AstraZeneca and Daiichi Sankyo’s collaborative commercial and medical strategy, featuring active investigator engagement and extensive data sharing, is driving increased awareness and adoption of Dato-DXd.

 

2. Expansion Across Key Indications

  • Non-Small Cell Lung Cancer (NSCLC): Dato-DXd is under active development for previously treated metastatic NSCLC, targeting patients with limited treatment options following chemotherapy and immunotherapy.

  • Breast Cancer: Development is heavily focused on HR-positive/HER2-low and triple-negative breast cancer (TNBC), where ADCs are rapidly transforming treatment approaches.

  • Broader Solid Tumors: Development efforts are ongoing to target additional TROP2-expressing tumors, potentially expanding the treatable patient population.

  • Pipeline Expansion and Combination Approaches: Strategies such as combining with immune checkpoint inhibitors are anticipated to further extend the drug’s market potential.

The Dato-DXd Market Report offers projected sales forecasts for Dato-DXd for indications until 2034, categorized across the 7MM i.e. United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan. The report also provides extensive coverage and a competitive landscape analysis of competitors and marketed products indication. It also covers analyst views along with market drivers and barriers.

AstraZeneca and Daiichi Sankyo’s Dato-DXd is serving as a beacon of hope for the patients suffering from the Antibody Drug Conjugates.

 

Dato-DXd Recent Developments

  • In December 2025, The European Medicines Agency (EMA) validated the Type II Variation marketing authorization application for DATROWAY (datopotamab deruxtecan) as monotherapy for the first-line treatment of adult patients with unresectable or metastatic triple negative breast cancer (TNBC) who are not candidates for PD-1/PD-L1 inhibitor therapy.

  • In October 2025, Positive results from the TROPION-Breast02 Phase III trial showed DATROWAY (datopotamab deruxtecan) demonstrated a statistically significant and clinically meaningful improvement for the dual primary endpoints of overall survival (OS) and progression-free survival (PFS) compared to investigator’s choice of chemotherapy as 1st-line treatment for patients with locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC) for whom immunotherapy was not an option.

 

What is a Dato-DXd Prescribed for?

Dato-DXd (datopotamab deruxtecan) is prescribed for the treatment of advanced or metastatic solid tumors, particularly non-small cell lung cancer (NSCLC) and breast cancer. It is an antibody–drug conjugate (ADC) that targets TROP2, a protein highly expressed on many cancer cells, delivering a potent chemotherapy payload directly to tumors. Dato-DXd is mainly intended for patients with previously treated, unresectable, or metastatic disease, especially those who have progressed after standard therapies.

The report extensively covers the details and developments related to Dato-DXd, capturing important highlights on developmental pipeline, regulatory status and special designations of Dato-DXd, route of administration, safety and efficacy details.

 

Do you know your drug’s competitive positioning against Dato-DXd? Dato-DXd Drugs Insights

 

Dato-DXd Market Assessment

This report provides a detailed market assessment of Dato-DXd for Antibody Drug Conjugates in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2028 to 2034.

 

Dato-DXd Clinical Assessment

The report provides the clinical trials information of Dato-DXd for Antibody Drug Conjugates covering trial interventions, trial conditions, trial status, start and completion dates. Report also includes important insights on regulatory milestones and other developmental activities related.

 

Dato-DXd Competitive Landscape

The report offers insights into the key players and companies actively engaged in the development of the specified indication. It provides valuable information regarding the competitive positioning of the Dato-DXd.

 

Dato-DXd Market Size in the US

A dedicated section of the report focuses on the expected market size of Dato-DXd for the United States. DelveInsight’s analysis includes market trends, growth projections, and key factors influencing the market dynamics, offering a comprehensive perspective for stakeholders.

 

Key Highlights of Dato-DXd:

  • The report contains forecasted sales of Dato-DXd for indication till 2034.

  • Comprehensive coverage of the late-stage emerging therapies for Antibody Drug Conjugates.

  • The report also features the qualitative and quantitative analysis with analysts as well as KOL views for Dato-DXd in Antibody Drug Conjugates.

 

Stay ahead in competition by leveraging insights on Dato-DXd market Report: Download the sample for Dato-DXd Market Report

 

Why you should buy Dato-DXd Market Report:

  • The report provides future market assessments for Dato-DXd for Antibody Drug Conjugates in the 7 Major Markets, Advance qualitative analysis like SWOT, expert analysts’ views, detailed overview of market competitors, and short analysis of other emerging therapies in Ulcerative Colitis.

  • Leading Dato-DXd for Antibody Drug Conjugates forecasted market data will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Dato-DXd

  • Discover the competitive landscape of Dato-DXd through 7MM

  • Get a Thorough Analysis of the Dato-DXd Development pipeline, Safety & Efficacy of the Dato-DXd, and ROA

  • Thorough Dato-DXd market forecast will help understand how drug is competing with other emerging Dato-DXd

  • Get analysis of the Dato-DXd clinical trial advancements and the detailed clinical assessment, regulatory and commercial assessment

  • Drug Market forecasts are calculated after taking into consideration KOL viewpoints

 

Related Reports By DelveInsight:

Antibody Drug Conjugates Pipeline

DelveInsight’s, Antibody Drug Conjugates Pipeline Insight, 2025 report provides comprehensive insights about 180+ companies and 290+ pipeline drugs in Antibody Drug Conjugates pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products.

It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

 

About DelveInsight

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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