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DelveInsight’s “Polymyalgia Rheumatica Market Insights, Epidemiology, and Market Forecast – 2034” report delivers an in-depth understanding of the Polymyalgia Rheumatica, historical and forecasted epidemiology and the Polymyalgia Rheumatica market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

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Key Takeaways from the Polymyalgia Rheumatica Market Report

• In December 2025, Novartis Pharmaceuticals conducted a study is to assess the safety and tolerability of secukinumab when administered long-term in patients with polymyalgia rheumatica. The study will consist of an up to 4-week screening period, an up to 2-year Treatment Period which includes two Treatment Periods, and a 16-week treatment-free follow-up period (20 weeks post last dose of secukinumab).
• According to the analysis, the number of individuals living with polymyalgia rheumatica in the US is projected to grow during the forecast period (2025–2034). This rise stems from an aging population, increased life expectancy among older adults, and greater recognition of the condition in routine health assessments.
• According to the secondary research, the age-adjusted prevalence of polymyalgia rheumatica in the US is approximately 701 cases per 100,000 individuals aged 50 years and older.
• As per the secondary research, higher rates in females at 870 per 100,000 and in males at 508 per 100,000.
• As per the secondary research, approximately 15% of patients with PMR develop giant cell arteritis (GCA), and 40-50% of patients with GCA have associated PMR.
• The leading Polymyalgia Rheumatica Companies such as Roche, Bristol Myers Squibb, Eli-lilly, Novartis, AbbVie, Sparrow Pharmaceuticals, Chugai Pharma, AbbVie, Janssen Research & Development, Sint Maartenskliniek, and others
• Promising Polymyalgia Rheumatica Therapies such as Tocilizumab, Abatacept, Baricitinib, Secukinumab, ABBV-154, SPI-62, TCZ, Upadacitinib, Guselkumab, Rituximab, and others

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Polymyalgia Rheumatica Epidemiology Segmentation in the 7MM

• Total Prevalent Cases of Polymyalgia Rheumatica
• Total Diagnosed Prevalent Cases of Polymyalgia Rheumatica
• Gender-specific Diagnosed Prevalent Cases of Polymyalgia Rheumatica
• Treated Cases of Polymyalgia Rheumatica

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Polymyalgia Rheumatica Marketed Drugs

• KEVZARA (sarilumab): Regeneron Pharmaceuticals

KEVZARA (sarilumab) is a fully human monoclonal antibody developed by Regeneron and Sanofi that targets and inhibits both soluble and membrane-bound interleukin-6 receptors (IL‑6R). It is the first and only biologic approved by the FDA specifically for adults with polymyalgia rheumatica who are inadequate responders to corticosteroids or cannot tolerate tapering. By blocking IL‑6 signaling, KEVZARA significantly reduces inflammation and disease activity, enabling more patients to achieve steroid-free remission, with supportive evidence from the Phase III SAPHYR trial showing nearly threefold higher sustained remission rates compared to placebo

Polymyalgia Rheumatica Emerging Drugs

• SPI-47: Sparrow Pharmaceuticals

SPI-47, is an investigational oral treatment for polymyalgia rheumatica (PMR) that combines low-dose prednisolone with clofutriben (SPI-62), a targeted 11β-HSD1 inhibitor. This combination is intended to deliver the anti-inflammatory benefits of steroids while minimizing their long-term side effects by reducing cortisol activation in tissues such as bone, muscle, and liver. Currently in Phase IIa trials, SPI-47 is being studied as a potential steroid-sparing therapy to improve the safety and effectiveness of PMR treatment.

• COSENTYX (secukinumab): Novartis

Secukinumab developed by Novartis is a fully human IgG1 monoclonal antibody that neutralizes interleukin‑17A (IL‑17A), a key cytokine driving inflammation. It is now being investigated as a treatment for polymyalgia rheumatica (PMR). In PMR, secukinumab is being studied for its potential to reduce inflammation and lower dependence on corticosteroids. A Phase III clinical trial (REPLENISH) is evaluating its effectiveness in achieving steroid-free remission in patients with relapsing PMR when combined with a short course of glucocorticoids.

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Polymyalgia Rheumatica Companies

Roche, Bristol Myers Squibb, Eli-lilly, Novartis, AbbVie, Sparrow Pharmaceuticals, Chugai Pharma, AbbVie, Janssen Research & Development, Sint Maartenskliniek, and others

Polymyalgia Rheumatica Market Outlook

Treatment options for polymyalgia rheumatica primarily focus on controlling inflammation and relieving symptoms, with low-dose corticosteroids, such as prednisone, being the standard and most effective first-line therapy. While newer insights have emerged such as the role of IL-6 in inflammation major therapeutic breakthroughs have been limited, and most treatment strategies still revolve around careful steroid tapering over months to years. In patients who relapse frequently or are steroid-intolerant, off-label use of immunosuppressants like methotrexate or biologics such as KEVZARA (sarilumab) is considered.

Scope of the Polymyalgia Rheumatica Market Report

• Coverage- 7MM
• Study Period- 2020-2034
• Polymyalgia Rheumatica Companies- Roche, Bristol Myers Squibb, Eli-lilly, Novartis, AbbVie, Sparrow Pharmaceuticals, Chugai Pharma, AbbVie, Janssen Research & Development, Sint Maartenskliniek, and others
• Polymyalgia Rheumatica Therapies- Tocilizumab, Abatacept, Baricitinib, Secukinumab, ABBV-154, SPI-62, TCZ, Upadacitinib, Guselkumab, Rituximab, and others
• Polymyalgia Rheumatica Therapeutic Assessment: Polymyalgia Rheumatica current marketed and Polymyalgia Rheumatica emerging therapies
• Polymyalgia Rheumatica Market Dynamics: Polymyalgia Rheumatica market drivers and Polymyalgia Rheumatica market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies
• Polymyalgia Rheumatica Unmet Needs, KOL’s views, Analyst’s views, Polymyalgia Rheumatica Market Access and Reimbursement

From market size to emerging drugs, find it all in our latest report. Read now! @ Polymyalgia Rheumatica Ongoing Clinical Trials Analysis

Table of Content

1. Key Insights

2. Report Introduction

3. Polymyalgia Rheumatica Market Overview at a Glance

4. Polymyalgia Rheumatica Epidemiology and Market Methodology

5. Executive Summary

6. Key Events

7. Polymyalgia Rheumatica: Disease Background and Overview

8. Polymyalgia Rheumatica Epidemiology and Patient Population

9. Patient Journey

10. Polymyalgia Rheumatica Marketed Drugs

11. Polymyalgia Rheumatica Emerging Drugs

12. Polymyalgia Rheumatica: Market Analysis

13. Key Opinion Leaders’ Views

14. Polymyalgia Rheumatica SWOT Analysis

15. Polymyalgia Rheumatica Unmet Needs

16. Polymyalgia Rheumatica Market Access and Reimbursement

17. Appendix

18. DelveInsight Capabilities

19. Disclaimer

About Us

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